Authored by Zachary Stieber via The Epoch Times (emphasis ours),

Federal regulators on Thursday approved the first gene therapy to restore hearing, just two months after the therapy’s maker formally requested a license.

The Food and Drug Administration approved the Regeneron therapy, Otarmeni, for children and adults with severe or profound hearing loss associated with OTOF gene variants.

The approval came 61 days after Regeneron filed for a biologics license, under a new effort known as the Commissioner’s National Priority Voucher Program that emphasizes quickly reviewing applications for products that address unmet needs.

“Today’s approval is a significant milestone in the treatment of genetic hearing loss,” Dr. Marty Makary, the FDA’s commissioner, said in a statement.

“Through the national priority voucher pilot program, the agency is accelerating therapies for rare diseases with unmet medical needs while proving we can successfully review even the most complex submissions—such as novel dual vector gene therapies and combination products requiring coordination across multiple offices and centers—in significantly shortened timeframes.”

Genetic mutations account for about half of cases of inherited hearing loss. Variants in the OTOF gene account for 2 to 8 percent of those cases.

To treat deafness, Otarmeni is administered to each ear using a syringe and catheter provided in the accompanying kit.

Regulators approved Regeneron’s therapy after reviewing data from a clinical trial involving 24 patients aged 10 months to 16 years. Of the 20 patients included in the efficacy analysis, 80 percent experienced improvement in hearing after receiving Otarmeni.

Common side effects of the drug included ear infection, nausea, and dizziness.

Dr. A. Eliot Shearer, an otolaryngologist at Boston Children’s Hospital and an investigator in the trial, said in a statement released by Regeneron that the one-time therapy provides “remarkable hearing improvements.”

“I’ve witnessed firsthand my trial participant responding to their mother’s voice, dancing to music and interacting with the world, and these moments are now possible for more children born with this specific form of hearing loss,” he said.

Regeneron said it will provide the therapy free of charge to patients in the United States as part of a deal struck with President Donald Trump and announced on Thursday.

Dr. George D. Yancopoulos, president and chief scientific officer of Regeneron, said in a statement that Otarmeni was an “unprecedented breakthrough” in gene therapy.

“Otarmeni is a huge scientific leap and is representative of Regeneron’s approaches to continually push the boundaries of science to benefit humanity,” he said.

“This unprecedented breakthrough in gene therapy has already proven to be life-changing for many of the children in our clinical trial and their families. We are honored to be in the position to be the first company to ever offer such a gene therapy advance for free to those in the U.S. and serves to highlight our belief that the biopharmaceutical industry can be a genuine force for good in the world.”

The U.S. military’s 55-day war with Iran has alarmingly drawn down several categories of high-end air-delivered munitions, forcing the Department of War to draw from critical stockpiles in Asia and Europe. The drawdown of these weapons only suggests a possible readiness problem and helps explain why President Trump’s war economy is set to accelerate, with expected increases in munitions production. 

The New York Times has released a report that says since the US-Iran conflict began in late February, the US military has burned through roughly 1,100 JASSM-ER long-range stealth cruise missiles, more than 1,000 Tomahawk cruise missiles, over 1,200 Patriot interceptors, and more than 1,000 Precision Strike and ATACMS missiles.

“The Iran war has significantly drained much of the U.S. military’s global supply of munitions, and forced the Pentagon to rush bombs, missiles and other hardware to the Middle East from commands in Asia and Europe,” the outlet said, citing internal Defense Department estimates and congressional officials.

The report continued, “The drawdowns have left these regional commands less ready to confront potential adversaries like Russia and China, and it has forced the United States to find ways to scale up production to address the depletions, Trump administration and congressional officials say.” 

Senator Jack Reed of Rhode Island, the top Democrat on the Armed Services Committee, stated earlier this week, “At current production rates, reconstituting what we have expended could take years.” 

One of the first major signals that the DoW was set to call on private industry to begin ramping up Trump’s war economy was a report earlier this month that said the Trump administration was exploring whether U.S. manufacturers, including GM, Ford, GE Aerospace, and Oshkosh, could convert civilian industrial capacity into weapons production as multiple conflict areas across Eurasia drag on and deplete critical weapons stockpiles.

The historical precedent is that America converted its automotive base during World War II to produce record numbers of main battle tanks, bombers, and fighter planes to win the war.

“The United States has many munitions with adequate inventories, but some critical ground-attack and missile-defense munitions were short before the war and are even shorter now,” Mark F. Cancian, a retired Marine Corps colonel and a senior adviser at the Center for Strategic and International Studies, told the outlet. He recently published a study estimating US weapons stockpiles.

Evidence of converting underused civilian industrial capacity has recently emerged, with the German automaker Volkswagen set to transform its Lower Saxony factory from producing T-Roc Cabriolets to manufacturing parts for the Iron Dome missile interceptor system.

The important signal we are gathering here is that the US may have to convert underutilized civilian industrial capacity, including truck and auto production lines, to weapons output.

To be frank, this is no longer peacetime procurement. It is wartime industrial mobilization, with Washington now being forced to confront the gap between the weapons it burns in the Middle East and the weapons its defense base can actually replace.

Authored by Zachary Stieber via The Epoch Times (emphasis ours),

The head of the Centers for Medicare and Medicaid Services (CMS) demanded that states across the nation take action to crack down on fraud in Medicaid, one of the federal government’s health insurance programs.

In letters to state Medicaid directors, CMS Administrator Dr. Mehmet Oz said they should develop and file with his agency a comprehensive strategy to ensure that Medicaid providers are legitimate.

“Corrupt individuals and organizations masquerading as health care providers are defrauding Medicaid, and American taxpayers, of billions of dollars each year, placing valuable resources out of reach for those the program was intended to serve: low-income senior citizens, children, and disabled individuals,” Oz wrote.

Oz had recently previewed the effort, saying it would involve proving whether the providers “actually exist.”

“I love Medicaid; I cannot say that more fervently,” Oz said at a summit held by Politico. “If you love something, you protect it. You don’t let it get defrauded. You don’t let it get taken advantage of.”

If states do not take action, then audits may be an option, he said.

CMS has been investigating Medicaid and Medicare, and officials have said they have identified billions in fraudulent or potentially fraudulent spending, leading to actions such as deferring $259 million in payments to Minnesota. They have had to clarify some claims, including acknowledging an error in calculations regarding New York.

The new letters said CMS is acting under its responsibilities outlined in federal law, including the Social Security Act, and that CMS understands that states face challenges administering the complex Medicaid program. Oz said in the letters that CMS analyses are suggesting “a persistent and growing Medicaid threat posed by sophisticated actors knowingly exploiting these complex systems for financial gains.”

“A foundational element of Medicaid program integrity is ensuring that only legitimate, qualified providers are enrolled and participating in the program,” Oz said. “Confirming that each state maintains accurate and regularly updated provider enrollment information is a critical foundation of CMS’ efforts to safeguard Medicaid program integrity, as it supports effective screening, monitoring, and oversight of participating providers.”

States were instructed to notify CMS of revalidation plans within 10 days and to follow up within 30 days with the strategy to make sure that providers are valid. It did not include any audit threats for noncompliance.

CMS declined to comment on the letters.

Oz added in a video statement that criminals are costing billions in taxpayer funds each year, and taking resources away from the needy.

“Here’s the bottom line: It’s time to make sure that providers of high-risk services are valid and meet all the requirements to deliver care to Medicaid beneficiaries,” Oz said in the video.

States have the ability to define which providers are high-risk, which might include providers without national identifiers, according to Oz.

“These are the gaps that criminals, including foreign nationals, exploit,” he said. “Revalidation works. It forces accountability, it removes bad actors, and it sends a clear message that the Medicaid system is not an unguarded piggy bank.”

Hard red winter wheat climbed to a two-year high by the end of the week, as our coverage of the drought shock now hitting America’s Breadbasket raises serious alarm bells on commodity desks.

The concern is not just reduced crop yields and quality. It is colliding with fertilizer shortages and elevated diesel prices, creating a broader inflationary transmission channel that could work its way through the food supply and translate into higher supermarket prices down the road.

Hard red winter wheat rose another 1% on Friday, with gains for the week approaching 6%. Active futures contracts in Chicago are now at their highest level since June 2024. Contracts are up 28% on the year.

On Thursday, UBS analysts, led by Jonathan Pingle, told clients that the drought conditions impacting the U.S. agricultural belt rank among the worst in more than 130 years:

The National Oceanic and Atmospheric Administration’s Palmer Drought Severity Index hit its highest level for March since records started in 1895, and March was the third-driest month recorded, regardless of time of year, behind only the famed 1930s Dust Bowl: July and August 1934. Water levels on the Mississippi look fine, as the seasonal lows are typically in the fall, but river levels in Memphis sit 24 feet below this time last year.

Pingle warned clients, “All eyes have been focused on the Middle East, but another supply shock may be unfolding in U.S. agricultural production.”

Summary

• Avalanche of Friday morning headlines speculating on Iran FM travel to Pakistan, and potential US delegating arriving too, but much appears speculation.

• Third US aircraft carrier, the George HW Bush, has finally arrived in Mideast regional waters after taking the long way around Africa.

• Hegseth in presser renews call, highlighting main issue, for Iran: “All they have to do is abandon a nuclear weapon in meaningful and verifiable ways…“; Warns Iranians over continued mine-laying.

• Iran FM unveils diplomatic tour which could include Islamabad in order to prepare for 2nd round dialogue with Washington, as each side’s finger remains on the trigger.

*  *  *

More Speculation on Ghalibaf Resigning Negotiations Team

Tehran on Thursday rejected widespread reports that Parliament Speaker Mohammad-Bagher Ghalibaf as resigned from leadership of Iran’s negotiating team. But these reports have persisted into Friday, with Saudi-funded, London-based Iran International ‘newly’ reporting:

Mohammad Bagher Ghalibaf, head of Iran’s negotiating team with the United States, has stepped down amid internal disagreements, Iran International has learned.

According to information obtained by Iran International, Ghalibaf was reprimanded for attempting to include the nuclear issue in talks with Washington and was forced to resign.

Hardline figure Saeed Jalili could replace him, while Foreign Minister Abbas Araghchi is also seeking to take over the negotiations.

And yet the fact remains that no talks are as yet scheduled, with regional media now saying Iran FM Araghchi is about to tour different countries, including Oman and even will make a stop in Russia – and that this may include Islamabad. If so, reports say it could just be part of a preparatory phase to engage Washington directly again.

‘Breakthrough’ on 2nd Round Pakistan Talks(?)

After signaling all day yesterday that it has not decided to engage the United States in a second round of peace talks, Friday morning has seen a flurry of headlines out of Saudi and regional media speculating that today is different. “Iranian Foreign Minister Abbas Araghchi may arrive tonight accompanied by a small delegation,” Pakistani government source has told Al Arabiya’s correspondent.

Also Bloomberg too is reporting that Iran’s FM Araghchi is expected to arrive in Islamabad tonight. Additionally sources out of Pakistan say the country may announce today the resumption of negotiations between Iran and America. Of course, we’ve seen many such “second round of US-Iran talks expected” headlines before which didn’t materialize, and at the moment there’s no signs of movement out of the US side.

However, some of these same sources and headlines are cautioning that it is unclear if there will be Washington engagement. But if a second round of talks actually materializes, it will lend credence to the recent White House insistence that Tehran’s private stance is much more compromising and conciliatory than its public stance. Latest:

IRAN’S FOREIGN MINISTER ABBAS ARAGHCHI IS EXPECTED TO REACH ISLAMABAD AT AROUND 10 PM LOCAL TIME, ACCORDING TO AN IRANIAN SOURCE.

And Al Jazeera freshly reports on a flurry of phone calls, which suggests some kind of potential “breakthrough” in getting back to the negotiating table:

Government sources have confirmed there is a “high likelihood of a breakthrough” in US-Iran talks in Islamabad, as a delegation led by Iran’s Foreign Minister Abbas Araghchi is expected to arrive in the Pakistani capital tonight. Earlier today, Iran’s foreign minister held a telephone conversation with Pakistan’s Deputy Prime Minister and Foreign Minister Ishaq Dar, confirmed by both sides.

Pakistan’s Foreign Ministry said the two sides exchanged views on regional developments, the ceasefire, and ongoing diplomatic efforts in the context of US-Iran engagement. Dar underscored the importance of sustained dialogue, while Araghchi appreciated Pakistan’s “consistent and constructive facilitation role”, the ministry said.

Iran’s state news agency IRNA also reported that Araghchi held a separate telephone conversation with Pakistan’s Army chief Asim Munir.

Third US Carrier Finally Arrives in Region

US Central Command (CENTCOM) is flashing the big stick, as there are now three US aircraft carrier groups total in the region. Some pundits have speculated that the whole Islamabad second round talks back-and-forth has just been a delay tactic for each side to regroup, replenish missiles, and position forces in the region.

After all, Israel’s defense ministry on Thursday stated bluntly it is preparing for a new round of warfare with Iran, and Iranian forces too say they are ready for anything that comes, and have continued to preview that America’s Gulf allies would also face renewed attack for hosting US forces.

For the first time in decades, three aircraft carriers are operating in the Middle East at the same time. Accompanied by their carrier air wings, the USS Abraham Lincoln (CVN 72), USS Gerald R. Ford (CVN 78) and USS George H.W. Bush (CVN 77) include over 200 aircraft and 15,000… pic.twitter.com/fbMdz1IYn8

— U.S. Central Command (@CENTCOM) April 24, 2026

More Geopolitical Overnight & Latest

According to more of some of the latest from Al Jazeera:

• US President Donald Trump says he hopes to host Israeli and Lebanese leaders “in the near future”, after announcing a three-week extension to the fragile ceasefire in Lebanon, which was due to expire on Sunday.
• President Trump said he is under no pressure to end his war with Iran, though time is limited for Tehran. “I have all the time in the World, but Iran doesn’t – The clock is ticking!” Trump wrote on social media.
• A third US aircraft carrier has arrived in the Middle East. The USS George HW Bush joined the USS Gerald R Ford and USS Abraham Lincoln in a massive buildup of naval firepower.
• Trump gives orders to “shoot and kill” any Iranian boats placing sea mines in the Strait of Hormuz, as the US naval siege of Iran’s ports continues, and officials in Tehran say talks will not resume until the blockade is lifted.

And via Newsquawk: 

• Iran Foreign Minister to Visit Islamabad Friday, Pakistan Says; Oil Dips After Pakistan Says US-Iran Peace Talks Are Expected: BBG
• US President Trump posted that the meeting between Israel and Lebanon went well, the US is to work with Lebanon to protect itself from Hezbollah and that the Israel-Lebanon ceasefire is to be extended by three weeks: RTRS
• Israeli media: A limited operation against Iran may be carried out to avoid a prolonged war: Al Arabiya 
• An Iranian Ship Tried to Slip Past the Blockade. A U.S. Destroyer Chased It Down: WSJ
• Tanker Helga arrives at Iraq’s Basra offshore terminal to load 2mln BPD of crude, sources say; Helga is the second tanker to reach Basra terminals since the Hormuz closure.
• U.S. Soldier Charged With Using Classified Information to Bet on Maduro’s Ouster: WSJ
• Pentagon email floats suspending Spain from NATO, other steps over Iran rift: RTRS
• China to Curb US Investment in Tech Companies After Meta Deal: BBG
• Intel Shares Set to Eclipse Dot-Com Peak on Sales Forecast
• Conservative super PAC threatens to unseat Republicans over immigration bill: RTRS
• Hedge Fund at Center of Avis Squeeze Added to Stake Before Rout: BBG
• Citadel Sends Warning Shot to NYC After Mamdani Jabs Griffin: WSJ
• Meta Signs Multibillion-Dollar Deal With Amazon to Use Its CPU Chips for AI: WSJ
• Lilly’s New Obesity Pill Off to Slow Start in Race With Novo: BBG
• Oracle’s Deluge of AI Debt Pushes Wall Street to the Limit: WSJ
• Orban’s Son-in-Law Waits Out Hungarian Wealth Probe in New York: BBG
• Chinese Securities Regulator said that China is to allow qualified foreign investors to trade treasury futures from April 24, 2026, for hedging purposes only.
• US official said Russia is to be included in G20 summit invitations

* * *

China has newly placed a slew of EU defense and aerospace firms on a control list, or effectively a new blacklist, reportedly with an eye on Taiwan tensions. It has barred its exporters from supplying dual-use items to seven EU firms, including FN Herstal and Omnipol a.s., according to a statement from the Chinese commerce ministry.

The ministry said the measure targets European defense companies that previously sold arms to Taiwan or maintained links with it, and stated the restrictions will not affect normal economic and trade exchanges with the European Union.

Beijing said it will continue working with other countries to safeguard peace and maintain a stable global supply chain, in its usual boilerplate rhetoric directed at the West regarding Taiwan, which China sees as its own.

Other firms named include Hensoldt AG, Excalibur Army, SpaceKnow Inc., VZLU Aerospace, and FN Browning. The companies are mostly based in Czech Republic, Belgium, and Germany.

“The MOFCOM spokesperson emphasized that the legally mandated export control measures target only a small number of EU entities involved in military affairs, entities that have participated in arms sales to Taiwan island or colluded with Taiwan authorities, and the measures only target dual-use items,” state-run Global Times described further, in reference to China’s Ministry of Commerce. 

“They will not affect normal trade and economic exchanges between China and the EU, and law-abiding EU entities have absolutely nothing to worry about,” it added, citing the Commerce spokesperson.

All the while, Beijing has kept up its fiery denunciations, making clear there’s “no space” for ambiguity on what China sees as its territory (Taiwan).

Earlier this month, Chinese leader Xi Jinping had welcomed the leader of Taiwan’s main opposition party for a rare direct meeting in the Chinese capital.

The symbolism of the timing couldn’t be missed, as Xi invited Nationalist Party Chairwoman Cheng Li-wun to China ahead of the planned big mid-May summit with President Trump in which the Chinese leader could continue a push to dilute Washington’s support for Taiwan.

However, the Trump-Xi meeting is still anything but assured as moving forward, given the ongoing Iran war and very uneasy ceasefire with little evidence of an offramp in sight. 

Also, Washington has suddenly this week charged Beijing with stealing US artificial ​intelligence labs’ intellectual property on an “industrial scale”.

China’s Foreign Ministry on Taiwan:

There is but one China in the world. Taiwan is an inalienable part of China’s territory.

No one can stop the eventual reunification of China.

Reunification is presented as a matter of inevitability, not possibility.

Separatist attempts… pic.twitter.com/e0Xdz4bRyh

— Open Source Intel (@Osint613) April 22, 2026

The formal memo could upend the May summit before it even gets off the ground: “The US government has information indicating that foreign entities, principally based in China, are engaged in deliberate, industrial-scale campaigns to distil ​US frontier AI systems,” Michael Kratsios, director of the White House Office of Science ​and Technology Policy, wrote in a memo shared on social media on ⁠Thursday, per Reuters and FT.

Shares of Eli Lilly & Co. fell in New York premarket trading after new industry prescription data for the drugmaker’s blockbuster obesity shot Zepbound and recently approved oral weight-loss pill Foundayo disappointed Wall Street analysts.

Foundayo generated 3,707 prescriptions in its second week, according to new prescription-tracking data from IQVIA cited by RBC Capital Markets analysts. That compares with 18,410 prescriptions for Novo’s oral version of Wegovy during its second week after launch, suggesting Lilly’s weight-loss drugs are falling behind in the GLP-1 race.

“While we believe comparisons early into launch should be considered immaterial, Foundayo’s uptake this week is likely to be received negatively,” RBC Capital Markets analyst Trung Huynh wrote in a note to clients earlier.

In a separate note citing the IQVIA data, Cantor analyst Carter Gould said, “We see slower TRx (total prescriptions) growth continuing in the injectable segment across diabetes and obesity, though injectable Wegovy notably grew by 7% week over week.“

Gould noted, “While we are cautious to make definitive claims off of one week of launch data from IQVIA, we acknowledge that investors will be scrutinizing the numbers, and believe that Foundayo scripts totaling just 20% of what oral Wegovy achieved during their first full week could cause the stock to be weak today.”

Shares of Eli Lilly fell as much as 4% in premarket trading. Through Thursday’s close, the stock was down 14.6% for the year.

Danske Bank analysts wrote earlier that Novo might hold the lead in obesity pills because Wegovy is a much better product than competitors.

On Friday, President Donald Trump extended a temporary waiver of the century-old Jones Act (Merchant Marine Act of 1920) for an additional 90 days. The move allows foreign-flagged vessels to transport fuel, oil, fertilizer, and other essential goods between U.S. ports, aiming to stabilize domestic supply chains and ease price pressures stemming from the ongoing U.S.-Israeli war with Iran and resulting disruptions in the Strait of Hormuz.

White House Assistant Press Secretary Taylor Rogers announced the extension via social media, stating: “President Trump issued a 90-day extension to the Jones Act waiver. New data compiled since the initial waiver was issued revealed that significantly more supply was able to reach U.S. ports faster. This waiver extension provides both certainty and stability for the U.S. and global economies.” Rogers added that the administration has taken multiple steps to mitigate short-term energy market disruptions and ensure vital products continue flowing.

President Trump issued a 90-day extension to the Jones Act waiver.

New data compiled since the initial waiver was issued revealed that significantly more supply was able to reach U.S. ports faster.

This waiver extension provides both certainty and stability for the U.S. and…

— Taylor Rogers (@TaylorRogers47) April 24, 2026

This builds on the initial 60-day waiver issued on March 17 (effective until mid-May), which White House Press Secretary Karoline Leavitt described at the time as “another step to mitigate the short-term disruptions to the oil market” amid the conflict.

What Is the Jones Act?

The Jones Act requires that goods transported by water between U.S. ports be carried on vessels that are U.S.-built, U.S.-owned, U.S.-flagged, and primarily U.S.-crewed. Enacted in 1920 as Section 27 of the Merchant Marine Act, it was designed to protect and rebuild the American maritime industry following World War I, ensuring a domestic fleet capable of supporting national defense and commerce during emergencies.

Critics argue it limits vessel availability and raises shipping costs, while supporters say it preserves U.S. jobs, shipbuilding capacity, and strategic maritime independence. Waivers are rare and typically granted only for national defense or emergencies, often following requests from the Department of Defense or in response to natural disasters.

Historical precedents include waivers during World War I and II, the Korean War era, Hurricanes Katrina (2005), and other crises like the 2012 Alaska fuel emergency. More recent examples occurred after Hurricanes Harvey, Irma, and Maria in 2017.

The waiver stems directly from the U.S.-Israeli military campaign against Iran that began on February 28, 2026. U.S. and Israeli strikes targeted Iranian leadership, including the assassination of Supreme Leader Ali Khamenei, prompting Iranian retaliation with missile and drone attacks across the Middle East, strikes on U.S. bases and allies, and – critically – the closure (or severe restriction) of the Strait of Hormuz.

The Strait of Hormuz, through which roughly 20-25% of global seaborne oil and significant liquefied natural gas passes, became a major chokepoint. Iran’s actions, combined with a subsequent U.S. naval blockade of Iranian ports starting in mid-April, led to a collapse in tanker traffic (down over 90% at times), global oil price spikes (from ~$70/barrel pre-war to averages above $100 in March), fuel shortages in parts of Asia, and ripple effects on fertilizer and agricultural supply chains worldwide.

These disruptions exacerbated domestic U.S. fuel price pressures, prompting the administration to act on the Jones Act to reroute more Gulf Coast oil and refined products to other U.S. coasts via foreign tankers.

Impacts and Early Data

Early results from the initial 60-day waiver appear positive according to the White House. Officials report that foreign tankers moved approximately 9 million barrels of oil, boosting effective domestic shipping capacity by about 70% and accelerating deliveries to ports and refineries. Rogers and other spokespeople emphasized that “the data reveals more supply has reached U.S. ports faster,” helping mitigate cost increases.

The 90-day extension (expected to run from mid-May into mid-August) aims to provide longer-term certainty as the Iran conflict and Hormuz situation remain fluid, with fragile ceasefires and ongoing diplomatic efforts (including talks in Pakistan) showing limited progress.

The decision has drawn sharp criticism from the U.S. maritime industry. The American Maritime Partnership called the extension of what it termed a “historically long and ineffective” waiver “an affront to U.S. workers,” arguing it undermines domestic shipbuilding and seafarer jobs.

Proponents of the Jones Act maintain that repeated waivers erode the law’s protective intent, while energy and logistics groups see the temporary relief as a pragmatic response to an extraordinary crisis.

US equity futures jumped to a new all time high, reversing modest overnight losses, and oil tumbled to session lows on reports that Iran is sending a delegation to Pakistan today for talks, boosting hopes of ceasefire extension or more. Iranian Foreign Minister Araqchi is expected to arrive in Islamabad at 22:00 local time (1:00pm ET), the NY Post reports. As of 8:00am ET, S&P futures rallied as much a 0.6% to a new all time high of 7,190, reversing a modest loss in overnight trading as Brent tumbled from $107 to around $104 on the report. Tech shares rallied on the back of strong results from Intel and SAP SE, with the Nasdaq 100 up 1.3% and on track for a fourth straight weekly gain with most Mag 7 stocks trading higher. INTC added +29% amid surprises in both earnings and sales across all major businesses; the move will almost certainly extend the gains for semiconductor stocks to 18 straight days. The dollar slid 0.2%.  Brent erased gains to fall 1.2% to below $104 a barrel while WTI dropped $1.2 and is now at $94.68 after trading as high as $98 earlier. Treasuries advanced, with the 10-year yield down two basis points at 4.31%. Metals are mixed, gold rebound above $4700; ags are higher. Today’s macro data include the final UMich consumer sentiment survey. 

In premarket trading, Mag 7 stocks are mostly higher (Microsoft +1.2%, Amazon +0.9%, Alphabet +0.6%, Meta +0.6%, Apple -0.1%, Tesla +0.9%)

• Comfort Systems USA (FIX) climbs 7% after the HVAC company reported revenue that beat estimates.
• Coursera (COUR) falls 10% after the online education company’s first-quarter profit missed the average analyst estimate and the midpoint of its full-year revenue forecast also undershot expectations.
• Edwards Lifesciences (EW) gains 2% after the medical devices firm reported a first quarter adjusted earnings per share beat, and boosted its sales forecast for the full year.
• HCA Healthcare (HCA) falls 7% after the health-care services company reported net income for the first quarter that met the average analyst estimate.
• Hims & Hers Health (HIMS) climbs 4% after JPMorgan initiated the stock with an overweight rating, citing improving vitals for the telehealth firm.
• Intel (INTC) shares are up 27% — and on track to close at an all-time high if gains hold through regular trading — after the chipmaker delivered a blockbuster sales forecast.
• MaxLinear (MXL) jumps 43% after the semiconductor company’s first-quarter results and second-quarter revenue forecast were both better than expected.
• Organon & Co. (OGN) climbs 21% after the Economic Times reported that Sun Pharma is planning to submit a binding offer of $13 billion to acquire the US-based pharmaceutical company.
• Procter & Gamble (PG) gains 3% after the consumer-products maker reported stronger-than-expected results for its latest quarter, driven by growth in the beauty category.
• SLB (SLB) falls 3% after the oilfield services company reported adjusted earnings per share for the first quarter that matched the average analyst estimate. The company also agreed to buy S&P Global Geoscience & Petroleum Engineering portfolio.
• World Kinect Corp. (WKC) rises 22% after the fuel-services company reported adjusted earnings per share for the first quarter that beat the average analyst estimate.

In corporate news, DeepSeek rolled out preview versions of a new flagship AI model a year after upending Silicon Valley, calling it the most powerful open-source platform in a challenge to rivals from OpenAI to Anthropic. Cognition AI is said to be in early talks to raise a new round of funding that would more than double its valuation to $25 billion. Mercedes-Benz is assessing potential cybersecurity risks linked to Anthropic’s Mythos model, signaling that concerns over threats from AI bots are spreading beyond the financial sector into the industrial economy. SoftBank plans to transform part of its Osaka factory into a major battery production line to power its AI data centers. President Trump said he is considering having the US purchase Spirit Aviation, saying it could be a potentially good investment for the federal government. United Airlines CEO Scott Kirby on deals, fuel price spikes and turf wars is the subject of today’s

Sentiment was boosted this morning after Pakistani officials familiar with the matter said Iran’s foreign minister was expected in Islamabad on Friday (around 10pm local time), with a second round of talks between Tehran and Washington expected. S&P futures jumped to a record high just under 7,200 as Brent erased gains to fall 1.2% to below $104 a barrel; the dollar slid 0.2%. Treasuries advanced, with the 10-year yield down two basis points at 4.31%. Still, we’ve seen such premature hope fizzle before; meanwhile in the Middle East, a US-sanctioned supertanker laden with Iranian oil appeared to be attempting to cross the Strait of Hormuz on Friday, with traffic through the waterway otherwise at a virtual standstill. As usual, traders will watch for headlines and signals from the US and Iran, along with shipping flows, for clues on energy supply risks, with any Strait of Hormuz escalation likely to keep oil elevated.

Tech shares rallied on the back of strong results from Intel and SAP, with the Nasdaq 100 on track for a fourth straight weekly gain. Intel surged 29% in premarket trading on a blockbuster sales forecast. Taiwan Semiconductor Manufacturing jumped 5% in Taipei after regulators eased limits on single-stock fund holdings.

“Those who called the end of the AI trade made a big mistake, as we can see looking at the semiconductor space,” said Mabrouk Chetouane, head of global market strategy at Natixis Investment Managers. “The earnings growth is just astounding. It’s a sweet spot where the offer for chips can’t meet the demand.”

Barclays strategist Emmanuel Cau notes the “renewed AI frenzy has seen semis stocks surging, widening further the US/Asia vs Europe performance gap.” US equity strength is supported by technical factors, Bloomberg notes as it echoes what we have been saying since late March, adding that gross exposure is high, net exposure isn’t, and there’s still cash that needs to be put to work. Discretionary managers have benchmarks to beat and higher dispersion shows the earning season is leading to a resumption of micro over macro.

Resurgent optimism over the economic potential of artificial intelligence has powered semiconductor manufacturers to an unprecedented 17-day rally. Investors also see the sector as at little risk of spillover from the Iranian war, with corporate profits and outlooks outpacing expectations in most instances.

“One takeaway from this earnings season is that the US leadership is back because of its dominance in tech, and semiconductors notably,” said David Kruk, head of trading at La Financiere de l’Echiquier in Paris. “Investors are now focusing more on earnings than geopolitics and taking the view that eventually a peace deal will occur.”

Equity and bond funds attracted the bulk of inflows this week, with stocks and IG bonds already tracking record annualized inflows, Bank of America says. Equity funds drew $25.9 billion, with US inflows at $18 billion in the week through April 22, according to BofA citing EPFR Global data. 

In Europe, SAP climbed 5.5% after reporting cloud backlog growth that reassured investors amid AI disruption concerns. Still, the Stoxx 600 fell 0.1%, with sectors such as autos and retail hit on concern that the war in the Middle East will have a long-lasting impact on consumer  sentiment; the energy sector gained. Here are some of the biggest movers on Friday:

• SAP shares rise as much as 7.3% after reporting current cloud backlog — a crucial indicator for future revenue to be booked — maintained a 25% growth rate on constant-currency terms in 1Q, beating expectations.
• Volvo shares rise as much as 2.6% as the Swedish firm raised its outlook for the European truck market after orders increased. Morgan Stanley calls the results strong and stable.
• Telia gains as much as 3.9% after the Swedish telecommunications group reported earnings. Analysts say the mostly in-line print is a good start to the year, noting a slight beat to Ebitda as a key positive.
• Siemens Energy rises as much as 4.9%, setting a new record high, after the firm saw significant order beats for both its Gas Services and Grid Technologies divisions in the second quarter and increased its outlook for the full year.
• Adyen shares rise as much as 5.3% after agreeing a deal to buy Talon.One in its first ever acquisition. The deal, while small to Adyen’s scale, is a good starting point for the payments firm and should boost its unified commerce offerings, according to analysts.
• Coloplast shares extend losing streak into a fifth day, dropping as much as 3.5% to the lowest since February 2014, after issuing a profit warning for the full year.
• Electrolux falls as much as 25%, the most on record, after the Swedish home appliances group reported significantly weaker-than-expected 1Q figures, driven by poor performance in its key North American market.
• MTU Aero Engines shares fall as much as 4.8% as UBS downgrades the German aircraft engine manufacturer to sell from neutral, citing exposure to a hard landing as the aftermarket cycle turns.
• Safran shares fall as much as 3.6% as Oxcap lowers its recommendation on the aerospace and defense firm to equal-weight from overweight, citing concerns around global commercial flight growth.
• Mondi shares fall as much as 8.9% as higher costs and lower prices hit the packaging company’s first-quarter earnings.

Asian stocks edged higher as tech stock gains outweighed concerns over the progress of US-Iran peace talks and shipping flows in the Strait of Hormuz. The MSCI Asia Pacific Index rose as much as 0.5% after swinging between gains and losses Friday. The gauge is headed for its third week of gains, the longest streak since the Iran war started. Taiwan’s Taiex index was the best performer in the region, with TSMC leading gains to a fresh record, after the island’s financial regulator eased limits on single-stock fund holdings. Tech stocks were also buoyed by Intel’s stronger-than-expected sales outlook. Meanwhile, equity benchmarks in China, India and Indonesia slipped. Despite mild gains on Friday, risk appetite remains muted into the weekend as investors await further signals from Washington and Tehran for clues on energy supply risks. While elevated oil prices remain a key macro risk, traders are looking for selective opportunities in the artificial intelligence theme. In Japan, investors will be watching out for next week’s Bank of Japan meeting. The BOJ is leaning toward leaving its policy rate unchanged on April 28 amid lingering uncertainty over the war in Iran, according to people familiar with the matter.

Brent erased gains to fall 1.2% to below $104 a barrel. A Pakistani official familiar with the matter said Iran’s foreign minister was expected in Islamabad on Friday, with a second round of talks between Tehran and Washington expected. The dollar slid 0.2%.

In rates, treasuries advanced, with the 10-year yield down two basis points at 4.31%. European bonds underperform over the early London session, led by gilts following stronger-than-expected UK retail sales data. UK yields lead European bond weakness, trading cheaper by up to 5bp across front-end of the curve

US economic data calendar slate includes April University of Michigan sentiment (10am) and Kansas City Fed services activity (11am)

Market Snapshot

• S&P 500 mini 0.5%,
• Nasdaq 100 mini +1.3%,
• Russell 2000 mini 0.4%
• Stoxx Europe 600 -0.1%,
• DAX -0.1%,
• CAC 40 -0.6%
• 10-year Treasury yield +0.4 basis points at 4.31%
• VIX 18.69, -0.70 points
• Bloomberg Dollar Index -0.2%
• euro little changed at $1.1685
• WTI crude -1.4% at $94.5/barrel

Top Overnight News

• Iran Foreign Minister to Visit Islamabad Friday, Pakistan Says; Oil Dips After Pakistan Says US-Iran Peace Talks Are Expected: BBG
• US President Trump posted that the meeting between Israel and Lebanon went well, the US is to work with Lebanon to protect itself from Hezbollah and that the Israel-Lebanon ceasefire is to be extended by three weeks: RTRS
• Israeli media: A limited operation against Iran may be carried out to avoid a prolonged war: Al Arabiya 
• An Iranian Ship Tried to Slip Past the Blockade. A U.S. Destroyer Chased It Down: WSJ
• Tanker Helga arrives at Iraq’s Basra offshore terminal to load 2mln BPD of crude, sources say; Helga is the second tanker to reach Basra terminals since the Hormuz closure.
• U.S. Soldier Charged With Using Classified Information to Bet on Maduro’s Ouster: WSJ
• Pentagon email floats suspending Spain from NATO, other steps over Iran rift: RTRS
• China to Curb US Investment in Tech Companies After Meta Deal: BBG
• Intel Shares Set to Eclipse Dot-Com Peak on Sales Forecast
• Conservative super PAC threatens to unseat Republicans over immigration bill: RTRS
• Hedge Fund at Center of Avis Squeeze Added to Stake Before Rout: BBG
• Citadel Sends Warning Shot to NYC After Mamdani Jabs Griffin: WSJ
• Meta Signs Multibillion-Dollar Deal With Amazon to Use Its CPU Chips for AI: WSJ
• Lilly’s New Obesity Pill Off to Slow Start in Race With Novo: BBG
• Oracle’s Deluge of AI Debt Pushes Wall Street to the Limit: WSJ
• Orban’s Son-in-Law Waits Out Hungarian Wealth Probe in New York: BBG
• Chinese Securities Regulator said that China is to allow qualified foreign investors to trade treasury futures from April 24, 2026, for hedging purposes only.
• US official said Russia is to be included in G20 summit invitations

A more detailed look at global markets courtesy of Newsquawk

APAC stocks traded mostly in the red, ex. Nikkei 225, as bourses caught up to the selloff seen stateside, as risk-off flows dominated the tape after the reports that Israel is on high alert in anticipation of a possible renewed war this weekend. ASX 200 slipped further below the 8,800 handle, as losses in IT offset the gains made by Energy names. Nikkei 225 outperformed, supported by the tech sector as chips benefitted from Intel’s earnings (see more below). Ibiden, one of Japan’s biggest electronics companies, hit a new ATH while Canon fell after cutting its FY profitability guidance. Hang Seng and Shanghai Comp traded with the biggest losses, albeit just slightly, after a flurry of earnings. China Telecom reported Q1 net that fell by 17% Y/Y while autos underperformed.

Top Asian News

• Samsung Electronics (005930 KS) has produced the first working single-digit nanometer DRAM working die, TheLec reported citing sources; Co. intends to adjust processing conditions based on this.
• Nomura Holdings (8604 JT) FY25/26 (JPY): Net 362.1bln (prev. 340.7bln Y/Y), Pretax 539.8bln (prev. 432.1bln Y/Y), Revenue 4.76tln (prev. 4.74tln Y/Y). Cuts dividend.
• Hyundai Steel (004020 KS) Q1 (KRW) oper. profit 15.7bln (prev. loss 19.0bln Y/Y).
• Kia Motor (000270 KS) Q1 2026 (KRW): Net 1.83tln (exp. 1.93tln), Operating Profit 2.21tln (exp. 2.3tln), Revenue 29.5tln (exp. 29.3tln).
• Mercuria is to take a 25% stake in an aluminium smelter, as well as hunt for copper mining investments, the FT reported.
• Taiwan regulator is to increase the equity exposure limit per stock to 25% from 10% for funds and ETFs.
• Renesas (6723 JT) Q1 2026 (JPY): Revenue 380.3bln (prev. 308.8bln Y/Y) , Operating profit 90.6bln (prev. 21.5bln Y/Y).

European bourses started the European session with broad based losses, continuing the downbeat mood seen across APAC trade. From an index perspective, the IBEX 35 (-1.3%) lags peers, whilst the AEX (-0.1%) fares a bit better vs peers. European sectors hold a strong negative bias. Energy leads, buoyed by strength in underlying oil prices. Also for the sector, Siemens Energy  (+2.4%) gains post-earnings after it reported a mixed set of results, but raised its FY outlook; elsewhere, Eni (+1%) beat on its Adj. EBIT metric, and announced a 90% increase to its share buyback, citing an upbeat commodities outlook. Tech and Telecoms complete the top three. The Tech sector has been boosted today by post-earnings strength in SAP (+6.4%). The Co. reported better-than-expected operating profit and revenue, with cloud metrics also topping expectations. It also said it will buy back EUR 10bln of shares. To the bottom of the pile resides Autos, Basic Resources and Retail. The autos sector is underperforming this morning with seemingly broad-based losses; Volvo (+1%) reported Q1 metrics today, where its metrics were mixed, but ultimately indicating resilience amidst challenges.

Top European News

• German Ifo Current Conditions (Apr) 85.4 vs. Exp. 85.5 (Prev. 86.7, Low. 83, High. 87).
• German Ifo Business Climate (Apr) 84.4 vs. Exp. 84.8 (Prev. 86.4, Low. 83.7, High. 87.5).
• German Ifo Expectations (Apr) 83.3 vs. Exp. 83.9 (Prev. 86.0, Low. 82, High. 87.3).
• Spanish PPI YoY (Mar) Y/Y 3.4% (Prev. -7%).
• French Consumer Confidence (Apr) 84 vs. Exp. 88 (Prev. 89, Low. 87, High. 89).
• Hungarian Unemployment Rate (Mar) 4.7% (Prev. 4.9%).
• UK Retail Sales YoY (Mar) Y/Y 1.7% vs. Exp. 1.3% (Prev. 2.5%, Low. 0.8%, High. 2.2%).
• UK Retail Sales ex Fuel YoY (Mar) Y/Y 1.7% vs. Exp. 2.0% (Prev. 3.4%, Low. 1.5%, High. 2.5%).
• UK Retail Sales ex Fuel MoM (Mar) M/M 0.2% vs. Exp. 0.2% (Prev. -0.4%, Low. -0.5%, High. 0.6%).
• UK Retail Sales MoM (Mar) M/M 0.7% vs. Exp. 0.0% (Prev. -0.4%, Low. -0.8%, High. 1.8%).

Trade/Tariffs

• China reportedly to add seven EU companies to export control list, according to reported. Hensoldt (HAG GY) was added.
• Canada is reportedly to seek talks with the EU regarding access to ‘Made in Europe’ scheme, according to FT.
• China’s Commerce Minister met with the President of European Automotive Manufacturers Association to talk about the China-EU auto industry cooperation and EU trade restrictions. Commerce Minister stated that China will firmly safeguard Chinese firm’s rights.
• US President Trump tells the Telegraph that the US will retaliate if the UK continues to target companies such as Apple (AAPL) , Google (GOOGL) and Meta (META) through the digital services tax.
• US President Trump said the US will put a tariff on the UK if the digital service tax is not dropped.

FX

• FX price action is lacklustre on the final trading day of the week. DXY leads marginally, while CHF and JPY are slightly lower.
• DXY trades tentatively and broadly in tandem with oil prices. A light calendar ahead with the Fed on blackout ahead of next week’s meeting and only UoM final data on the docket. USD-specific news light, though the Japanese Finance Minister said overnight there were no plans to change currency swap lines with the US. DXY still remains supported above 100 and 200 DMAs at 98.50; upside resistance is 98.90, which marks the session high.
• SNB Chairman Schlegel was on the wires a couple of times. He said they have “unrestricted” room for manoeuvre when it comes to the policy rate and FX intervention – Vice Chair Martin also echoed these remarks. EUR/CHF is unchanged on the session; it attempted to approach 0.92, but the move faltered at 0.9199.
• Katayama is also on the wires, she said “will take decisive action on speculative activity”, JPY unchanged, in a signal that markets are becoming comfortable with the Finance Minister’s threats. USD/JPY unchanged, looks at 160 to the upside. BoJ rate decision next week, likely to remain on hold, with all eyes on Governor Ueda’s tone at the presser.
• GBP shrugged off strong UK Retail Sales for March, as it does not change the narrative into next week’s BoE, where a hold is the base case. The data showed upside was driven by an increase in fuel sales, with retailers reporting that motorists were filling their tanks when buying following the start of the Middle East conflict. Online sales saw upside and are potentially indicative of a robust spring sale period. However, the core figures were in line/softer-than-expected, and potentially point to some greater-than-expected caution among consumers during the early stages of the Middle East conflict. EUR/GBP and Cable both unchanged, the former on a 0.8670 handle.

Fixed Income

• A modestly bearish session for fixed benchmarks, initial action a function of the modest and since increasing energy upside as we count down to and participants position into a potentially risk-packed weekend.
• Amidst this, USTs post downside of a handful of ticks in a thin 110-30 to 111-03 band. Ahead, the US docket is light, and we look to next week’s FOMC.
• Bunds post slightly larger downside, perhaps as Dutch TTF has been leading oil benchmarks throughout the morning. Currently, in the red by c. 30 ticks but also in a relatively narrow 125.20-44 band. The European docket is light, aside from Italian supply (should be well received, particularly after the sizeable demand at last week’s syndications); as such, price action will likely be dictated by geopolitical developments.
• Gilts gapped lower at the open, acknowledging the pressure in fixed peers seen late-Thursday. Opened at 87.10, lower by 41 ticks. Thereafter, slipped another 28 to an 86.82 low and has held there since; the second bout of pressure spurred by further energy upside and a hawkish BoE DMP. The DMP spurred end-2026 BoE pricing to 59bps of tightening from c. 54bps this morning and significantly above the 23bps implied this time last week.
• To recap the day’s data. UK Retail Sales were strong on a headline level but in-line/soft on a core basis, with consumer motor fuel purchases driving the headline, no implications for the BoE next week (hold expected, guidance in focus). Thereafter, Germany’s Ifo was soft across the board, with no real follow-through to EGBs.
• Italy sold EUR 2.5bln vs exp. EUR 2.25-2.5bln 2.20% 2028 BTP Short Term: b/c 1.63x (prev. 1.78x) & average yield 2.80% (prev. 2.89%).
• Australia sold AUD 1bln vs exp. AUD 1bln 2.50% 2030 AGB: b/c 3.82x (prev. 3.44x), average yield 4.6947% (prev. 4.2888%).

Commodities

• In geopolitics, fresh updates have been light as focus remains on the state of the US-Iran ceasefire and talks. The week ahead centres on four key watchpoints. First, the Strait of Hormuz “red line”: President Trump has warned the US Navy could actively engage IRGC vessels suspected of laying mines or interfering with traffic, shifting from shadowing to potential direct strikes, particularly after an IRGC-escorted Iranian ship defied the blockade. Second, the nuclear deal standoff: Washington is pushing for a comprehensive deal, while Tehran insists the nuclear file is not part of the current talks, raising the risk that negotiations collapse if neither side compromises on uranium enrichment. Third, internal dynamics in Tehran: reports of leadership friction and IRGC influence over the negotiating team point to possible policy inconsistency or hardline escalation. Fourth, ceasefire fragility: despite the extended Israel-Lebanon truce, sporadic clashes and reported drone activity underline how easily a trigger event could occur.
• Oil rose for a fifth day as limited US-Iran progress towards resumed de-escalation talks kept supply concerns elevated; Brent climbed above USD 106/bbl (vs weekly lows of ~ USD 91/bbl) and is set for its biggest weekly gain since the war’s first week. WTI June, however, remains sub-USD 100/bbl. Brent currently trades in a daily range between 105.02-107.40/bbl while WTI resides in a USD 95.55-97.85/bbl range.
• Gold edged lower, below USD 4,970/oz, with investors weighing whether higher crude prices from the US-Iran conflict could keep inflation and interest rates elevated. XAU/USD resides in a USD 4,658.03-4,711.23/oz range at the time of writing.
• Copper heads for a weekly loss, with the broader base metals complex also mostly under pressure, as uncertainty over the Middle East war clouds the global growth outlook, while the US and Iran show little sign of returning to talks after Trump extended the ceasefire indefinitely, and the Strait of Hormuz remained largely blocked. 3M LME copper resides in a USD 13,215.58- 13,322.33/t. LME aluminium spread experiences the largest backwardation since 2024.
• Japanese PM Takaichi said she is urging the cabinet to seek new sources for oil imports.
• Union Spokesperson said workers at Australia’s INPEX (1605 JT) LNG plant vote in favour of strikes.
• EU leaders have tasked Finance Ministers to come up with new measures to deal with potential energy shortages after assessing that current proposals were not enough, Bloomberg reported, citing sources.
• Japan’s METI said Japan is to release 5.8mln kL of national oil reserves, starting May 1st.
• Imports of Russian fuel oil to Singapore has jumped with volume in April already more than double the average monthly amount in 2025, according to FT citing Vortexa data.
• The fire at Russia’s Tuapse oil terminal is under control.
• US President Trump said that the US does not have an oil shortage and are taking millions of barrels of oil from Venezuela. Have a great relationship with Venezuela.
• CME cuts initial margin on its Comex 100 gold futures to 6% from 7% and Comex 5000 silver futures to 11% from 14%.

Geopolitics: Middle East

• US President Trump posted that the meeting between Israel and Lebanon went well, the US is to work with Lebanon to protect itself from Hezbollah and that the Israel-Lebanon ceasefire is to be extended by three weeks.
• US President Trump said nobody is trying to get through the US blockade.
• US President Trump said the Israel-Lebanon talks in the Oval Office went well and it would be great to resolve simultaneously with Iran. Looking forward to the next meeting with Israeli PM Netanyahu. Great chance of peace between Israel and Lebanon this year. Everyone seems united against Hezbollah. Israel-Lebanon peace should be an easy one. Israel will have to defend itself if they are shot at. Israel will be surgical in their self-defence. Iran has to cut its Hezbollah funding.
• Tanker Helga arrives at Iraq’s Basra offshore terminal to load 2mln BPD of crude, sources say; Helga is the second tanker to reach Basra terminals since the Hormuz closure.
• “Israeli media: A limited operation against Iran may be carried out to avoid a prolonged war”, Al Arabiya reported.
• Pakistani official noted of a state of uncertainty regarding the second round of talks, “and we await Iran’s response”, Al Arabiya reported.
• Israel again attacks southern Lebanon, claiming retaliation for overnight rocket fire, Al Jazeera reported.
• Lebanese press Al-Jumhuriya noted of accelerated diplomatic efforts toward a Lebanon–Israel non-aggression agreement, driven by the US–Saudi–Egypt initiative, Journalist Kais reported. Plan revives idea of containing (not dismantling) Hezbollah’s weapons. Key proposed terms:. Israel withdraws to ceasefire line. Lebanese army deploys in south. Hezbollah moves north of Litani River. Start of weapons containment plan. Border disputes (Blue Line) adjusted. Prisoner releases, return of civilians, reconstruction. Deal would have international (especially US) guarantees. Coordination includes Iran to ensure Shiite/Hezbollah involvement. Parallel effort to resolve internal Lebanese political divisions. Saudi envoy pushing for meeting of Lebanon’s top leaders to create a unified position.
• “Iranian Foreign Ministry: Araqchi held two called with the Pakistani army chief and foreign minister to discuss a ceasefire.”, Al Araby reported.
• Iranian Vice President said any attack on oil wells will be met with strikes on attackers’ oil facilities; said it will be beyond “eye for an eye” response, Mehr News reported.
• Senior IRGC Commander said Tehran is secure and its borders are stronger than before, Press TV reported.
• The US has put a USD 10mln bounty on the leader of the Iran-backed Shiite militia group in Iraq, CBS reported.
• Lebanese media reported that Israel have conducted airstrikes on the town of Al-Qasir in southern Lebanon a few hours after US President Trump announced the 3-week ceasefire extension, IRIB reported.
• Israel’s ambassador to the UN said the extension of the Lebanon ceasefire is not 100% certain and that Israel is forced to answer every time a threat is detected, Tasnim reported citing CNN.
• US military are developing plans to target Iran’s Hormuz defences if the ceasefire fails, CNN reported.
• Israel-Lebanon talks have gotten underway in the White House, according to reported.
• Hezbollah said it has launched rockets at Israel’s Shtula region in response to Israel violating ceasefire and targeting towns in southern Lebanon.
• Israeli military said several launches crossed from Lebanon towards Israel were intercepted.
• An internal Pentagon email explores options to punishing NATO allies that the US believes failed to support the US operations against Iran, according to a US official. Options include:. Suspending Spain from NATO. Reviewing the US position on British claims to the Falkland Islands. Suspending difficult countries from important or prestigious positions at NATO.

Geopolitics: Ukraine

• Ukrainian authorities say a foreign-flagged ship bound for Odesa was attacked by Russian drones.
• Imports of Russian fuel oil to Singapore has jumped with volume in April already more than double the average monthly amount in 2025, according to FT citing Vortexa data.
• The fire at Russia’s Tuapse oil terminal is under control.
• US official said Russia is to be included in G20 summit invitations.

US Event Calendar

Markets are entering the final day of the trading week in a cautious mood as US-Iran tensions show no signs of easing while the Strait of Hormuz remains essentially closed. Ahead of the weekend, there have been no signs of further talks, with Trump saying the “I don’t want to rush myself” when it comes to making a deal, while also claiming that “whatever I’m doing, it seems to be working very well”. Meanwhile, we saw Iran’s President, Foreign Minister and Parliamentary Speaker share similar messages of regime “unity” in short succession last night, after Trump posts claimed “infighting” between “Hardliners” and “Moderates” in Iran. The rhetoric had also leant in an escalatory direction earlier yesterday, with Trump posting that he’d ordered the US Navy to shoot boats placing mines in the Strait of Hormuz. So all that has left lingering uncertainty, even as Israel and Lebanon have agreed overnight to extend their ceasefire by three weeks according to the White House.

From a market perspective, that means oil prices continue to grind higher, with Brent crude rising +3.10% yesterday and another +0.97% overnight to $106.09/bbl. Unlike many recent sessions, this also weighed on US equities. The S&P 500 spiked lower just after Europe went home amid headlines that air defences had been activated in Tehran, before partially recovering to -0.41% by the close, with reports that this had been due to small drones rather than signifying a collapse of the ceasefire. Still, with the cacophony of headlines showing no signs of de-escalation, oil prices held onto most of their gains, while both 2yr (+3.6bps) and 10yr (+2.3bps) US Treasury yields closed higher on the day. We have seen some stablisation of these moves overnight, with both S&P 500 futures (-0.06%) and 10yr Treasury yields little changed.
In Asia, the Hang Seng (-0.20%), the CSI (-0.85%), the Shanghai Composite (-0.56%), the S&P/ASX 200 (-0.28%), and the KOSPI (-0.36%) are all in negative territory. In contrast, the Nikkei (+0.61%) is being boosted by tech, even in light of slightly stronger inflation figures from Japan. Core consumer prices increased by +1.8% year-on-year in March, up from +1.6% in February, a tenth ahead of expectations. Headline and core-core were inline. The BOJ is scheduled to convene next week, where it is anticipated that it will maintain current interest rates, while also signaling a potential readiness to raise rates.

Back to yesterday and oil’s gains extended across the futures curve. The 6-month Brent future (+2.34%) reached a 3-week high of $86.74/bbl as investors geared up to facing a more prolonged period of high energy prices. The pressures were even more visible in downstream products with US wholesale gasoline prices (+3.10%) reaching their highest level since 2022. This was echoed in near-term inflation swaps as well, with the 1yr Eurozone inflation swap (+16.2bps) surging up to 3.35%, whilst the 1yr US inflation swap (+8.6bps) rose to 3.32%, with the latter now only 6-7bps below its high on March 20.  

The exception to the overall cautious mood were semiconductor stocks. The Philadelphia semiconductor index (+1.71%) posted a record 17th consecutive advance, having now risen by an astonishing +41.1% over that run. See my CoTD yesterday here for more. The positive mood for chipmakers continued overnight after Intel’s Q2 sales guidance came in well above expectations ($13.8-14.8bn vs $13bn expected). Its shares surged by +20% in after-hours trading, helping NASDAQ futures to a +0.39% gain overnight.

The broader tech mood had been more downbeat in yesterday’s session, with the NASDAQ (-0.89%) underperforming and the Mag-7 (-1.56%) posting its biggest decline in four weeks. Meta (-2.31%) lost ground after announcing plans to cut 10% of its workforce, while Microsoft (-3.97%) announced voluntary buyouts that could cover up to 7% of its employees. There is a sense that these job losses are there to offset huge capex spend. Tesla slid by -3.56% after its results the previous evening.

In terms of yesterday’s other news, we saw a notable divergence between the US and European data with the release of the flash April PMIs. Strong US data raised hopes that the economy’s resilience was holding up into Q2. In fact, the flash composite PMI for April moved up to 52.0 (vs. 50.6 expected), with both the manufacturing (54.0) and services prints (51.3) coming in above expectations, while the subindices also pointed to rising price pressures. This saw markets dial down remaining Fed cut pricing, with a cut by year-end now only 20% priced, down from 30% at Wednesday’s close. 

Over in Europe, the PMIs told quite a different story, with clear weakness across much of the continent. Most notably, the Euro Area composite PMI fell to 48.6 (vs. 50.1 expected), which was a 17-month low and beneath the 50 mark that separates expansion from contraction. So that confirmed fears that Europe was headed for a more obvious stagflationary hit from the rise in energy prices. Indeed, that showed up in the price components, with input prices rising at their fastest since December 2022, and output prices at their fastest since March 2023.  

Given the stagflationary implications of the PMIs, European assets struggled to gain much traction yesterday before the US sell-off. Moreover, investors priced in a growing chance of ECB hikes to deal with the price shock, and the amount of hikes priced by December was up +10.5bps on the day to 59bps. Nevertheless, sovereign bond yields were broadly steady as higher inflation expectations were offset by lower real rates on the back of the growth fears. So 10yr bund yields were unchanged at 3.01%, while 10yr OATs (+0.7bps) and BTPs (+1.3bps) saw slight increases. Otherwise, the STOXX 600 (+0.05%) was basically flat, finally stabilising after three consecutive declines.
Here in the UK, gilts continued to underperform yesterday, with the 10yr yield (+3.0bps) up to 4.94%, whilst the 30yr yield (+3.6bps) hit a 7-month high of 5.61%. In part, that came as the political speculation around PM Starmer’s position continued to swirl. But the UK also saw a clear outperformance in the PMIs, with an unexpected increase that went against the pattern in the Euro Area. For instance, the composite PMI was up to 52.0 (vs. 49.8 expected), with a rise in both manufacturing (53.6) and services (52.0). So that added to expectations that the Bank of England would hike rates this year, with markets now pricing in 55bps of hikes by the December meeting, up +4.3bps on the day.

Looking at the day ahead, data releases include the Ifo Institute’s business climate indicator from Germany, and in the US there’s the University of Michigan’s final consumer sentiment index for April. Central bank speakers include the ECB’s Panetta, whilst today’s earnings include Procter & Gamble.

Chinese AI startup DeepSeek has launched a preview version of its long-awaited V4 model, ending months of silence from one of China’s most closely watched AI labs and arriving a year after its R1 release sparked U.S. market turmoil and concerns across Silicon Valley AI firms.

The rollout signals that DeepSeek is full steam ahead in the frontier-model race:

DeepSeek-V4 Preview is officially live & open-sourced! Welcome to the era of cost-effective 1M context length.

• DeepSeek-V4-Pro: 1.6T total / 49B active params. Performance rivaling the world’s top closed-source models.

• DeepSeek-V4-Flash: 284B total / 13B active params. Your fast, efficient, and economical choice.

🚀 DeepSeek-V4 Preview is officially live & open-sourced! Welcome to the era of cost-effective 1M context length.

🔹 DeepSeek-V4-Pro: 1.6T total / 49B active params. Performance rivaling the world’s top closed-source models.
🔹 DeepSeek-V4-Flash: 284B total / 13B active params.… pic.twitter.com/n1AgwMIymu

— DeepSeek (@deepseek_ai) April 24, 2026

The open-source model comes in the V4 Flash and V4 Pro series, with DeepSeek saying its V4 “leads all current open models, trailing only Gemini-3.1-Pro.”

In terms of reasoning, the startup said it “beats all current open models in Math/STEM/Coding, rivaling top closed-source models.”

DeepSeek-V4-Pro

🔹 Enhanced Agentic Capabilities: Open-source SOTA in Agentic Coding benchmarks.
🔹 Rich World Knowledge: Leads all current open models, trailing only Gemini-3.1-Pro.
🔹 World-Class Reasoning: Beats all current open models in Math/STEM/Coding, rivaling top… pic.twitter.com/D04x5RjE3L

— DeepSeek (@deepseek_ai) April 24, 2026

Counterpoint Research Vice President Neil Shah told CNBC that “DeepSeek’s V4 preview is a serious flex.”

According to Counterpoint Principal AI Analyst Wei Sun, V4’s benchmark profile suggests the model could deliver “excellent agent capability at significantly lower cost.”

Ivan Su, Senior Equity Analyst at Morningstar, told CNBC that V4’s debut is unlikely to deliver the same market shock as R1 did a little more than a year ago, largely because Wall Street has already priced in the view that Chinese AI can be built and deployed at a lower cost.

Goldman analyst Christopher Moniz commented on the market reaction in overnight trading in China, where “GPU and domestic chip stocks rallied after DeepSeek unveiled preview versions of its latest V4 AI model.”

Moniz continued, “News of DeepSeek’s latest AI model created weakness in AI application names – Minimax (100 HK) -9.4% and Knowledge Atlas (2513 HK) -9.1%. Conversely, China domestic chipmakers spiked – HHS (1347 HK) +15.2% and SMIC (981 HK) +10%. Tencent (700 HK) -0.4% on mixed feedback regarding its new Hy3 model release, with locals noting it is less efficient than Minimax M2.7 launched a month ago”

One key question is the chip stack behind V4: which chips it was trained on and which hardware it runs on during inference. Huawei has already claimed that its latest AI computing cluster, powered by Ascend AI processors, can support V4, suggesting that Beijing’s domestic AI hardware ecosystem is powering DeepSeek’s ongoing frontier-model push.